How does the test detect low sperm concentration?
The OVRY™ Male Fertility Test is a qualitative immunoassay for the detection of sperm SP10 protein in semen. Based on anatomical, genetic and biochemical characteristics, sperm SP10 protein has been proven as an analyzer for sperm concentration detection. It is only expressed in the testis and is a differentiation marker, the last step in spermatogenesis. Sperm SP10 protein concentration and sperm concentration have a linear relationship; research has shown that when sperm concentration is more than 15 million sperm per milliliter that SP10 protein detection showed positive.
In the test procedure, SP10 monoclonal antibody is immobilized in the test line region of the device. After a specimen is placed in the specimen well, it reacts with SP10 monoclonal antibody-coated particles that have been applied to the specimen pad. This mixture migrates chromatographically and interacts with the immobilized SP10 monoclonal antibody. This mixture binds to the SP10 monoclonal antibody in the test when SP10 protein is equal to or greater than 15 million sperm per milliliter, indicating a positive result.
Related Articles
How important is sperm concentration to fertility?
According to the World Health Organization (WHO), the main factors affecting male infertility are sperm concentration, semen volume, total sperm count, liquefaction, sperm pH, sperm motility and sperm morphology. Therefore, a definitive diagnosis for ...
Is the darkness of the Test line (T) and/or Control line (C) relevant? Does a weaker line indicate lower sperm concentration?
The relative strength/darkness of the test line (T) and the control line (C) is irrelevant and does not matter. To read the results, simply determine whether the control line (C) and the test line (T) are present.
How often should I test?
The full process of producing new sperm takes around 70 days. Since lifestyle factors (like diet, sleep, drug use, weight etc.) can impact sperm concentration, it is recommended that those trying to conceive test every 3-4 months.
What are the test limitations?
This test screens for sperm concentration by detecting SP10 protein in semen only. It does not test for any of the other factors affecting sperm fertility. A negative test result does not prove male infertility and a positive result does not prove ...
How do I read my OVRY™ Male Fertility Test results?
Please refer to the instructions for a diagram to supplement the following descriptions. POSITIVE: Two distinct red or pink lines appear. One line should appear in the control region (C), and the other should appear in the test region (T). A positive ...